Improved process for production of gabapentin intermediate

Details Improved process for production of gabapentin intermediate Improved process for production of gabapentin intermediate

C - Chemistry, Metallurgy

07

C

C07C 233/00 (2006.01) C07D 221/20 (2006.01)

Patent

CA 2427237

The invention relates to a novel process for producing a the intermediary compound .alpha., .alpha.', dicyano-.beta., .beta.- pentamethyleneglutarimide. The process includes the steps of reacting a ketone such as cyclohexanone with ethylcyanoacetate in the presence of ammonium hydroxide.

L'invention concerne un procédé nouveau de fabrication du composé intermédiaire .alpha., .alpha.', dicyano-.beta., .beta.-pentaméthylèneglutarimide. Ledit procédé consiste à faire réagir une cétone telle que cyclohexanone avec éthylcyanoacétate en présence d'hydroxyde d'ammonium.

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