A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4545 (2006.01) A61K 31/215 (2006.01) A61K 31/444 (2006.01) A61K 31/445 (2006.01) A61K 31/4709 (2006.01) A61K 31/5377 (2006.01) A61K 38/18 (2006.01) A61K 45/06 (2006.01) A61P 25/28 (2006.01) C12N 5/00 (2006.01) C07K 14/475 (2006.01) C07K 14/48 (2006.01)
Patent
CA 2270985
The present invention relates to methods and pharmaceutical compositions for stimulating the growth of neurites in nerve cells. The compositions comprise a neurotrophic amount of a compound and a neurotrophic factor, such as nerve growth factor (NGF). The methods comprise treating nerve cells with the above compositions or compositions comprising the compound without a neurotrophic factor. The methods of this invention can be used to promote repair of neuronal damage caused by disease or physical trauma.
L'invention porte sur des méthodes et des compositions pharmaceutiques stimulant la croissance des neurites des cellules nerveuses. Lesdites compositions comprennent une dose à effet neurotrophique d'un composé et d'un facteur neurotrophique tel que le facteur de croissance nerveuse (NGF). Lesdites méthodes consistent à traiter les cellules nerveuses à l'aide des susdites compositions ou de compositions comprenant le composé mais pas de facteur neurotrophique. Les méthodes de l'invention peuvent servir à promouvoir la réparation de lésions neuronales dues à une maladie ou à un traumatisme physique.
Su Michael
Zelle Robert E.
Smart & Biggar
Vertex Pharmaceuticals Incorporated
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