Pharmaceutical product for application to uterus mucosa

Details Pharmaceutical product for application to uterus mucosa Pharmaceutical product for application to uterus mucosa

A - Human Necessities

61

K

A61K 38/09 (2006.01) A61K 9/00 (2006.01) A61K 47/30 (2006.01)

Patent

CA 2233797

A drug comprising either a peptide having the LH-RH action or an LH-RH antagonist is carried on an intrauterine contraceptive device (IUD) so as to be able to provide controlled release. Once the IUD is put in the uterus, the carried drug is gradually released over such a prolonged period of treatment time as, for example, several months to be continuously absorbed through the uterus mucosa or the vagina mucosa. This construction makes it possible to reduce the patient's pain and such a troublesomeness as frequent drug administration and continuously administer a necessary drug over a prolonged period of time while taking a contraceptive measures.

Médicament comportant soit un peptide ayant une action LH-RH ou un antagoniste LH-RH est porté sur un dispositif de contraception intra-utérin (DIU) de manière à assurer une libération contrôlée. Une fois que le DIU est placé dans l'utérus, le médicament qu'il contient est libéré progressivement sur une période de traitement qui peut atteindre, par exemple, plusieurs mois pour être absorbé de façon continuelle à travers la muqueuse utérine ou vaginale. Cette construction permet d'atténuer la douleur et de réduire les inconvénients liés à l'administration fréquente de médicaments et d'administrer continuellement un médicament nécessaire sur une période prolongée tout en assurant la contraception.

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