Use of thrombin-derived peptides for the therapy of chronic...

A - Human Necessities – 61 – K

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A61K 38/48 (2006.01) A61P 17/02 (2006.01)

Patent

CA 2455756

Disclosed is a method of promoting healing of a chronic dermal skin ulcer, such as a diabetic ulcer, on a subject. The method comprises the step of contacting the chronic dermal skin ulcer with an effective amount of an agonist of the non-proteolytically activated thrombin receptor.

La présente invention concerne un procédé favorisant la cicatrisation d'un ulcère dermique chronique, tel qu'un ulcère diabétique, chez un sujet. Le procédé comporte l'étape de mise en contact de l'ulcère dermique chronique avec une quantité efficace d'un agoniste d'un récepteur de thrombine ne présentant pas d'activité protéolytique.

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