C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 495/04 (2006.01) A61K 31/38 (2006.01) A61K 31/505 (2006.01)
Patent
CA 2269815
The invention relates to thienopyrim-idine of the formula (I) as well as to their physiologically acceptable salts, wherein R1, R2, R3, R4, X and n have the meaning cited in Claim 1. Said compounds exhibit a phosphodiesterase V inhibition and can be used in the treatment of cardiovascular diseases and for the treatment and/or ther-apy potency disorders.
L'invention concerne des thiénopyrimidines de la formule (I) ainsi que leurs sels physiologiquement acceptables où R<1>, R<2>, R<3>, R<4>, X et n ont la signification donnée dans la revendication 1. Ces composés ont un effet inhibiteur de la phosphodiestérase V et peuvent être utilisés pour le traitement de maladies du système cardio-vasculaire et pour le traitement et/ou la thérapie de l'impuissance.
Christadler Maria
Jonas Rochus
Kluxen Franz-Werner
Schelling Pierre
Fetherstonhaugh & Co.
Merck Patent Gesellschaft Mit Beschraenkter Haftung
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