Thiadiazoline derivative

Details Thiadiazoline derivative Thiadiazoline derivative

C - Chemistry, Metallurgy

07

D

C07D 285/12 (2006.01) A61K 31/433 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2528433

Disclosed are thiadiazoline derivatives represented by the general formula (I): (I) [wherein R1 represents a hydrogen atom or the like; R2 represents a hydrogen atom, -COR5 (wherein R5 represents a lower alkyl, etc.) or the like; R3 represents a lower alkyl or the like; R4 represents an aryl or the like; A represents -(CH2)n- (wherein n is an integer of 1-6) or the like; and B represents -NR6R7 (wherein R6 and R7 may be the same or different and represent hydrogen atoms, lower alkyls, etc.) or the like] and pharmacologically acceptable salts thereof.

Dérivés de thiadiazoline de formule générale (I) dans laquelle R?1¿ représente un atome d'hydrogène ou analogue, R?2¿ représente un atome d'hydrogène, -COR?5¿ (dans laquelle R?5¿ représente un alkyle inférieur, etc.) ou analogue, R?3¿ représente un alkyle inférieur ou analogue, A représente (CH¿2?)¿n?- (dans laquelle n est un nombre entier de 1 à 6) ou analogue, et B représente NR?6¿R?7¿ (dans laquelle R?6¿ et R?7¿ peuvent être identiques ou différents et représentent des atomes d'hydrogène, des alkyles inférieurs, etc.) ou analogue. La présente invention concerne également des sels acceptables sur le plan pharmaceutique desdits dérivés.

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