Preparation process of new thieno-triazolo-diazepine

Details Preparation process of new thieno-triazolo-diazepine Preparation process of new thieno-triazolo-diazepine

C - Chemistry, Metallurgy

07

D

167/210, 260/239

C07D 495/22 (2006.01) A61K 31/55 (2006.01)

Patent

CA 2013516

This invention relates to a preparation process of the thieno-triazolo-diazepine derivatives of the formula: Image wherein Y stands for oxygene or sulphur and R stands for various substituents, consisting in reacting the thieno-triazolo-diazepine compound of the formula A: Image on the appropriate R - N = Y derivative, then reacting the resulting compound on hydrazine-hydrate and, finally, cyclizing the compound thus obtained with triethylortoacetate.

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