Imidazo pyridine derivatives which inhibit gastric acid...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/435 (2006.01)

Patent

CA 2329921

The present invention relates to imidazo pyridine derivatives of formula (I), in which the phenyl moiety is substituted, and in which the imidazo pyridine moiety is substituted with carboxamide group in 6-position, which inhibit exogenously or endogenously stimulated gastric acid secretion and thus can be used in the prevention and treatment of gastrointestinal inflammatory diseases.

L'invention concerne des dérivés d'imidazo pyridine de la formule (I) dans laquelle la fraction phényle est substituée et dans laquelle la fraction imidazo pyridine est substituée par un groupe carboxamide en position 6. Ces dérivés inhibent la sécrétion d'acide gastrique de stimulation exogène ou endogène et ainsi peuvent être utilisés dans la prévention et le traitement de maladies inflammatoires gastro-intestinales.

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