Compounds for immunotherapy and diagnosis of breast cancer...

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 15/12 (2006.01) A61K 35/12 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 9/02 (2006.01) C12N 15/62 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2365912

Compounds and methods for the treatment and diagnosis of breast cancer are provided. The inventive compounds include polypeptides containing at least a portion of a breast tumor protein. Vaccines and pharmaceutical compositions for immunotherapy of breast cancer comprising such polypeptides, or polynucleotides encoding such polypeptides, are also provided, together with polynucleotides for preparing the inventive polypeptides.

L'invention concerne des composés et des procédés pour le traitement du cancer du sein. Les composés décrits renferment des polypeptides qui contiennent au moins une partie de protéine de tumeur du sein. L'invention concerne en outre des vaccins et des compositions pharmaceutiques pour l'immunothérapie du cancer du sein, qui renferment ces polypeptides, ou des polynucléotides codant ces polypeptides. L'invention concerne enfin des polynucléotides intervenant dans la préparation des polypeptides considérés.

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