C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 7/02 (2006.01) A61K 39/00 (2006.01) A61K 39/285 (2006.01) A61K 48/00 (2006.01) C12N 15/863 (2006.01)
Patent
CA 2676149
The present invention relates to methods for purification of Vaccinia viruses (W) and/ or Vaccinia virus (W) particles, which can lead to highly pure and stable virus preparations of predominantly biologically active viruses. The invention encompasses purifying a virus preparation in a sterilized way with high efficiency and desirable yield in terms of purity, biological activity and stability, aspects advantageous for industrial production.
L'invention concerne des procédés de purification de virus Vaccinia (W) et/ou de particules de virus Vaccinia (W), qui permettent d'obtenir des préparations virales stables et d'une haute pureté à base de virus biologiquement actifs principalement. L'invention consiste à purifier une préparation virale de manière stérilisée, avec une efficacité élevée et un rendement souhaitable en termes de pureté, activité biologique et stabilité, aspects qui sont avantageux dans la production industrielle.
Djurup Rene
Post Hansen Sara
Bavarian Nordic A/s
Shapiro Cohen
LandOfFree
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