Oral diclofenac preparation

Details Oral diclofenac preparation Oral diclofenac preparation

A - Human Necessities

61

K

A61K 31/195 (2006.01) A61K 9/24 (2006.01) A61K 9/50 (2006.01) A61K 31/196 (2006.01)

Patent

CA 2071319

ABSTRACT OF THE DISCLOSURE The novel diclofenac preparation with control- led release is in the form of pellets. The active ingredient, applied to inert pellets, is coated with a membrane layer which contains, in addition to 35-65% by weight of a water-insoluble polymer, 5-20% by weight of at least one water-soluble and/or water-insoluble pore- forming agent and 20-50% by weight of adjuncts. The pore-forming agents permit a very uniform release of diclofenac such that administration twice a day is sufficient. A film coating resistant to gastric juice is applied over the membrane layer.

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