Quinazoline and pyrido¬2,3-d|pyrimidine inhibitors of...

Details Quinazoline and pyrido¬2,3-d|pyrimidine inhibitors of... Quinazoline and pyrido¬2,3-d|pyrimidine inhibitors of...

C - Chemistry, Metallurgy

07

D

C07D 417/12 (2006.01) A61K 31/00 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) A61K 31/513 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61K 31/522 (2006.01) A61P 17/06 (2006.01) A61P 19/02 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01) A61P 37/06 (2006.01) C07D 239/80 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01) C07D 473/00 (2006.01) C07D 473/16 (2006.01) C07D 487/04 (2006.01) C07D 491/10 (2006.01) C07D 498/10 (2006.01)

Patent

CA 2450724

Quinazoline and pyrido[2,3-d]pyrimidine phosphodiesterase 7 (PDE 7) inhibitors of the following formula [insert chemical structure here] wherein R1, R2, L, Y1, Y2, Y3 and Z are as described herein, are provided which are useful in treating T-cell mediated diseases.

L'invention concerne les inhibiteurs de quinazoline et de pyrido[2,3-d]pyrimidine de la phosphodiestérase 7 (PDE 7), représentés par la formule suivante, dans laquelle R?1¿, R?2¿, L, Y?1¿, Y?2¿, Y?3 ¿et Z sont tels que décrits dans l'invention, et utilisés dans le traitement des maladies associées aux lymphocytes T.

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