Islet cells from human embryonic stem cells

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/071 (2010.01) C12N 5/0735 (2010.01) A61K 35/39 (2006.01) A61P 3/10 (2006.01) C12M 3/06 (2006.01) C12P 21/00 (2006.01) C12P 21/02 (2006.01) C12Q 1/02 (2006.01) C07K 14/62 (2006.01)

Patent

CA 2692325

This disclosure provides a system for producing pancreatic islet cells from embryonic stem cells. Differentiation is initiated towards endoderm cells, and focused using reagents that promote emergence of islet precursors and mature insulin-secreting cells. High quality populations of islet cells can be produced in commercial quantities for use in research, drug screening, or regenerative medicine.

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