Process for preparing 2,4-dioxo-3-azabicyclo[3.1.0]hexanes

Details Process for preparing 2,4-dioxo-3-azabicyclo[3.1.0]hexanes Process for preparing 2,4-dioxo-3-azabicyclo[3.1.0]hexanes

C - Chemistry, Metallurgy

07

D

C07D 209/52 (2006.01)

Patent

CA 2209684

A process for preparing a compound of formula (I): (see fig.I) wherein R is C1-C6 alkyl, C3-C6 cycloalkyl or benzyl, and wherein the phenyl moiety of said benzyl group is optionally substituted with one or two substituents each independently selected from halo, nitro, C1-C6 alkyl, C1-C6 alkoxy, amino and trifluoromethyl, which comprises treating a solution of a compound of formula (II): (see fig.II) wherein R is as defined for formula (1), and a halonitromethane in a first organic solvent, with a quaternary ammonium fluoride of formula (III): (see fig.III) wherein R1, R2, R3 and R4 are each independently selected from C1-C8 alkyl and benzyl, optionally in solution in a second organic solvent.

Préparation d'un composé de formule (I) (voir fig. I), où R est un alkyle C1-C6, un cycloalkyle C3-C6 ou un benzyle, et où la fraction phényle du benzyle renferme facultativement un ou deux substituants, choisis chacun indépendamment parmi les groupes halo, nitro, alkyle C1-C6, alcoxy C1-C6, amino et trifluorométhyle, comprenant le traitement d'une solution d'un composé de formule (II) (voir fig. II), où R a la définition de la formule (1), et un halonitrométhane dans un premier solvant organique, avec un flurorure d'ammonium quaternaire de formule (III) (voir fig. III), où R1, R2, R3 et R4 sont choisis chacun indépendamment parmi un alkyle C1-C8 et un benzyle, facultativement en solution dans un second solvant organique.

Affiliated with

Also associated with

Rating

Process for preparing 2,4-dioxo-3-azabicyclo[3.1.0]hexanes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for preparing 2,4-dioxo-3-azabicyclo[3.1.0]hexanes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparing 2,4-dioxo-3-azabicyclo[3.1.0]hexanes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1853997