Percutaneous pharmaceutical preparation

Details Percutaneous pharmaceutical preparation Percutaneous pharmaceutical preparation

A - Human Necessities

61

K

167/166, 167/198

A61K 31/565 (2006.01) A61K 9/70 (2006.01) A61K 47/12 (2006.01) A61K 47/14 (2006.01) A61K 47/24 (2006.01)

Patent

CA 2000401

A percutaneous pharmaceutical preparation in tape form is provided. The preparation comprises a flexible backing, which is not permeable to an active ingredient, and an adhesive layer formed on the flexible backing, the adhesive layer comprising an adhesive base material and an active ingredient compatible with the adhesive base material, wherein the adhesive base material consists essentially of a copolymer containing 2-ethylhexyl acrylate in a con- centration of 45 to 80 mol% and N-vinyl-2-pyrrolidone in a concentration of 20 to 55 mol%, and the active ingredient is estradiol and/or the esters thereof which are contained in a concentration of 6 to 25% by weight of the total amount of the adhesive base material and the active ingredient.

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