Herpesvirus vaccines

Details Herpesvirus vaccines Herpesvirus vaccines

A - Human Necessities

61

K

A61K 39/245 (2006.01) C07K 14/03 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2141574

A herpesvirus vaccine comprising a mutated herpesvirus suspended in a pharmaceutically acceptable carrier. The mutated herpesvirus is capable of infecting cells of the mammal to be vaccinated, but incapable of completing a replicative cycle, and it is capable of eliciting a protective immune response in that mammal. The mutation occurs in at least one gene encoding a protein essential for replication of the virus, so that the mutation renders the virus replication defective.

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