Aryl and heterocyclic cyanoguanidine derivatives

Details Aryl and heterocyclic cyanoguanidine derivatives Aryl and heterocyclic cyanoguanidine derivatives

C - Chemistry, Metallurgy

07

D

C07D 213/75 (2006.01) A61K 31/275 (2006.01) A61K 31/33 (2006.01) C07C 275/28 (2006.01) C07C 279/28 (2006.01) C07D 215/38 (2006.01) C07D 217/22 (2006.01) C07D 233/88 (2006.01) C07D 235/08 (2006.01) C07D 263/56 (2006.01) C07D 277/64 (2006.01) C07D 307/66 (2006.01) C07D 333/36 (2006.01)

Patent

CA 2132770

Abstract ARYL AND HETEROCYCLIC CYANOGUANIDINE DERIVATIVES Compounds having the formula I Image and pharmaceutically acceptable salts thereof wherein R1 to R4 and n are as defined herein and X is O, S or NCN. These compounds have potassium channel opening activity and are useful, therefore for example, as cardiovascular agents.

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