Novel high affinity human antibodies to tumor antigens

Details Novel high affinity human antibodies to tumor antigens Novel high affinity human antibodies to tumor antigens

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 51/10 (2006.01) C07K 16/30 (2006.01) C07K 16/32 (2006.01) C07K 16/46 (2006.01) C07K 19/00 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2245835

This invention provides for novel human antibodies that specifically bind to c- erbB-2. The antibodies may be used alone or as components of chimeric molecules that specifically target and deliver effector molecules to cells overexpressing c-erbB-2.

Cette invention porte sur de nouveaux anticorps humains qui se lient de manière spécifique à c-erbB-2. On peut utiliser ces anticorps seuls ou comme composants de molécules chimères agissant de manière spécifique en tant que molécules ciblantes et apportant des molécules effectrices à des cellules surexprimant c-erbB-2.

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