Bacterial delivery system

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/85 (2006.01) A61K 31/70 (2006.01) A61K 39/112 (2006.01) A61K 48/00 (2006.01) C12N 1/20 (2006.01) C12N 1/36 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2231332

This invention relates to a method of introducing functional nucleic acids into cells using a bacterial delivery system. The delivery system can be used as a vaccine to prevent or treat infectious diseases. This invention can be applied to any desired bacteria including attenuated strains of Shigella.

Cette invention se rapporte à un procédé pour introduire des acides nucléiques fonctionnels dans des cellules au moyen d'un système d'apport bactérien. Ce système d'apport peut être utilisé comme vaccin pour prévenir ou traiter des maladies infectieuses. Cette invention peut s'appliquer à n'importe quelle bactérie désirée, y compris des souches atténuées de Shigella.

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