Polynucleotides encoding cellular transporters and methods...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) C07K 14/705 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2431517

This disclosure encompasses the Indy gene, polypeptides encoded by the Indy gene and fragments thereof. This disclosure also encompasses homologs of the Indy gene both from Drosophila and other organisms. In addition, this disclosure encompasses the use of Indy polynucleotides, INDY proteins and polypeptides, antibodies to the INDY protein, antagonists that inhibit Indy activity or expression, and agonists that increase Indy activity or expression, in the diagnosis or treatment of body weight disorders or longevity in humans and animals.

This disclosure encompasses the Indy gene, polypeptides encoded by the Indy gene and fragments thereof. This disclosure also encompasses homologs of the Indy gene both from Drosophila and other organisms. In addition, this disclosure encompasses the use of Indy polynucleotides, INDY proteins and polypeptides, antibodies to the INDY protein, antagonists that inhibit Indy activity or expression, and agonists that increase Indy activity or expression, in the diagnosis or treatment of body weight disorders or longevity in humans and animals.

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