C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/38 (2006.01) C07K 14/705 (2006.01) C07K 14/81 (2006.01) C07K 16/40 (2006.01) C12N 5/20 (2006.01) C12N 9/64 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2267660
The invention relates to monoclonal antibodies against a human ACT and serine protease complex, preferably ACT-PSA presenting no cross reactivity to free, non-complexed human ACT and free, non-complexed PSA, as well as diagnostic test methods to detect serine protease ACT complexes, using these monoclonal antibodies.
L'invention concerne des anticorps monoclonaux contre un complexe d'ACT humain et d'une sérine-protéase, de préférence d'ACT-PSA, ne présentant sensiblement aucune réactivité croisée par rapport à l'ACT humain libre non complexé et au PSA libre non complexé, ainsi que des méthodes d'essai diagnostiques pour la détection de complexes de sérines-protéase-ACT, en particulier de PSA-ACT, avec utilisation de ces anticorps monoclonaux.
Deeg Rolf
Gallusser Andreas
Hubner-Parajsz Christa
Kaufmann Martin
Kientsch-Engel Rosemarie
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Roche Diagnostics Gmbh
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