Arylsulfatase

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

195/123, 195/39,

C12N 9/16 (2006.01) A61K 47/48 (2006.01) C12N 1/20 (2006.01)

Patent

CA 2027977

The present invention relates to an arylsulfatase of microbial origin. The enzyme may be linked to an antibody against a tumor-associated antigen and the resulting conjugate used in conjuction with a sulfated prodrug of a 4'-demethylepipodophyllotoxin glucoside derivative, particularly etoposide in cancer chemotherapy.

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