Antibodies specific for human prostate glandular kallikrein

Details Antibodies specific for human prostate glandular kallikrein Antibodies specific for human prostate glandular kallikrein

C - Chemistry, Metallurgy

07

K

C07K 16/40 (2006.01) C12N 9/64 (2006.01) C12N 11/00 (2006.01) G01N 33/543 (2006.01) G01N 33/573 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2165672

The present invention provides an isolated preparation of monoclonal or polyclonal antibodies which react specifically with human prostate-specific glandular kallikrein (hK2), but which do not cross-react with human prostate-specific antigen (PSA), as well as immunogenic hK2 antigens useful to provide such antibodies.

La présente invention se rapporte à une préparation iodée d'anticorps monoclonaux ou polyclonaux qui réagissent spécifiquement avec la kallicréine glandulaire humaine spécifique de la prostate (hK2), mais qui n'ont pas de réaction croisée avec l'antigène humain spécifique de la prostate (PSA). Des antigènes d'hK2 immunogènes aptes à produire de tels anticorps sont également décrits.

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