Vaccine for infectious agents, composition for treating and...

Details Vaccine for infectious agents, composition for treating and... Vaccine for infectious agents, composition for treating and...

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 31/70 (2006.01) A61K 39/00 (2006.01) A61K 39/385 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/155 (2006.01) C07K 16/18 (2006.01) G01N 33/564 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2223825

A vaccine for treating and/or preventing infectious diseases where the infectious agent has at least one intracellular phase in the host during its multiplication cycle, is disclosed. The vaccine comprises at least one cryptic epitope of a cellular element that is carried along by an intracellular infectious agent as it leaves the cell, and revealed by said infectious agent. A composition for treating and/or preventing HIV infections, antibodies to a peptide of interest, and a diagnostic method, are also disclosed.

La présente invention concerne un vaccin destiné au traitement et/ou à la prévention de maladies d'origine infectieuse, l'agent infectieux ayant au moins une phase intracellulaire chez l'hôte lors de son cycle de multiplication, caractérisé en ce qu'il comporte au moins un épitope cryptique d'un élément cellulaire emporté par un agent infectieux intracellulaire lors de son passage à l'extérieur de la cellule et qui est dévoilé par l'agent infectieux. Elle concerne également une composition destinée au traitement ou à la prévention des infections à HIV, des anticorps dirigés contre un peptide d'intérêt et un procédé de diagnostic.

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