C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/435 (2006.01) C07D 207/08 (2006.01) C07D 207/09 (2006.01) C07D 471/04 (2006.01)
Patent
CA 2095361
Optically pure isomers of the following formula (see formula I) which are 7-[3-(1,1-dialkylmethyl-1-amino)-1- pyrrolidinyl]quinolones and naphthyridones as therapeutically active and safe antibacterial agents are described, as well as pharmaceutical compositions thereof, and a method of treating bacterial infections therewith. Also described is a method of manufacture of the quinolones and naphthyridones as well as the starting materials, the optically pure pyrrolidine moieties for attachment at the 7-position.
Hagen Susan Elizabeth
Suto Mark James
Macrae & Co.
Warner-Lambert Company
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