Use of compounds with a nitrogen-oxygen heterocycle as...

Details Use of compounds with a nitrogen-oxygen heterocycle as... Use of compounds with a nitrogen-oxygen heterocycle as...

A - Human Necessities

61

K

A61K 31/675 (2006.01) A61K 31/42 (2006.01) A61K 31/422 (2006.01) A61K 31/4439 (2006.01) A61K 31/535 (2006.01) A61K 31/5355 (2006.01) A61K 45/06 (2006.01) A61P 31/00 (2006.01) A61P 33/00 (2006.01)

Patent

CA 2369526

The invention relates to the use of compounds of general formula (I), whereby Y is a C1-3 alkenylene group; B is selected from the group comprised of C1-26 alkenylene groups, whereby one C atom can be substituted by an oxygen atom and one C atom can be substituted by a sulfur atom, or two C atoms can be replaced by an S heterocycle, and; X represents the phosphororganic group (a) or the amino group (b). The inventive compounds are used for inhibiting the 1-desoxy- D-xylulose-5-phosphate-(DOXP) metabolic pathway, are used as a herbicide, and for producing a medicament. The invention also relates to method for therapeutically and prophylactically treating infections in humans and animals caused by viruses, bacteria, fungi and parasites.

L'invention concerne l'utilisation de composés de la formule générale (I) pour inhiber la voie métabolique du 1-désoxy-D-xylulose-5-phosphate-(DOXP). Y désigne un groupe alkénylène, B est sélectionné dans le groupe comprenant des groupes alkénylène C¿1-26?, un atome de C pouvant être remplacé par un atome d'oxygène et un atome de C pouvant être remplacé par un atome de soufre ou deux atomes de C pouvant être remplacés par un hétérocycle S, et X désigne le groupe phosphoro-organique (a) ou le groupe amino (b). L'invention concerne en outre l'utilisation de ces composés comme herbicide et pour préparer un médicament, ainsi qu'un procédé de traitement thérapeutique et prophylactique d'infections chez l'homme et l'animal, induites par des virus, des bactéries, des champignons et des parasites.

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