Method for inhibiting retinoid skin damage

Details Method for inhibiting retinoid skin damage Method for inhibiting retinoid skin damage

A - Human Necessities

61

K

A61K 31/5377 (2006.01) A61K 31/07 (2006.01) A61K 31/11 (2006.01) A61K 31/191 (2006.01) A61K 31/203 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01)

Patent

CA 2370236

Erb inhibitors used in combination with retinoids are effective to prevent skin injury otherwise caused by retinoids alone. A method of treating skin aging and similar skin disorders comprises administering retinoids in combination with erb inhibitors of the general formula <SEE FORMULA I> where E1, E2, and E3 include halo, aryl is an alkylcarbonyl or alkenylcarbonyl, and alkoxy is lower alkoxy optionally substituted with amino groups.

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