C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 221/20 (2006.01) A61K 31/438 (2006.01) A61P 3/10 (2006.01) C07D 401/06 (2006.01) C07D 413/06 (2006.01) C07D 471/10 (2006.01) C07D 491/107 (2006.01)
Patent
CA 2661503
This invention relates to novel compounds of the Formula (I*), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof which are useful for the therapeutic treatment of diseases associated with the modulation or inhibition of 11.beta.- HSDl in mammals. The invention further relates to pharmaceutical compositions of the novel compounds and methods for their use in the reduction or control of the production of Cortisol in a cell or the inhibition of the conversion of cortisone to Cortisol in a cell.
Cette invention concerne de nouveaux composés de formule (I*), des sels acceptables du point de vue pharmaceutique de ceux-ci et des compositions pharmaceutiques de ceux-ci, lesquels sont utiles pour le traitement thérapeutique de maladies associées à la modulation ou à l'inhibition de la 11.beta.-HSD1 chez des mammifères. L'invention concerne en outre des compositions pharmaceutiques des nouveaux composés et des procédés d'utilisation de ceux-ci dans la réduction ou la régulation de la production de cortisol dans une cellule ou l'inhibition de la conversion de cortisone en cortisol dans une cellule.
Cacatian Salvacion
Claremon David A.
He Wei
Simpson Robert
Singh Suresh B.
Gowling Lafleur Henderson Llp
Vitae Pharmaceuticals Inc.
LandOfFree
Inhibitors of 11.beta. -hydroxysteroid dehydrogenase type 1 does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Inhibitors of 11.beta. -hydroxysteroid dehydrogenase type 1, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Inhibitors of 11.beta. -hydroxysteroid dehydrogenase type 1 will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1862590