Benzimidazolone derivatives for the treatment of urinary...

A - Human Necessities – 61 – K

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A61K 31/496 (2006.01)

Patent

CA 2642101

The invention relates to compositions comprising benzimidazolone derivatives of formula (I), optionally in form of the free base or in form of the pharmacologically acceptable acid addition salts thereof and methods of treating or preventing urinary incontinence, comprising the administration of a therapeutically effective amount of compound of formula (I). wherein R1, R2, R3, and R4 denote hydrogen or hydroxy with the proviso tha R1. R2, R3, and R4 cannot simultaneously represent hydrogen, optionally in form of the free base or in form of the pharmacologically acceptable acid addition salts thereof.

L'invention concerne des compositions comprenant des dérivés de benzimidazolone de formule (I), éventuellement sous forme de la base libre ou sous forme des sels d'addition acides pharmacologiquement acceptables de ceux-ci et des procédés de traitement ou de prévention de l'incontinence urinaire, comprenant l'administration d'une quantité thérapeutiquement efficace d'un composé de formule (I) dans laquelle R1, R2, R3 et R4 représentent hydrogène ou hydroxy, à condition que R1, R2, R3 et R4 ne représentent pas simultanément l'hydrogène, éventuellement sous forme des la base libre ou sous forme des sels d'addition acides pharmacologiquement acceptables de celui-ci.

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