Method for identifying type-i interferon responsive ms...

Details Method for identifying type-i interferon responsive ms... Method for identifying type-i interferon responsive ms...

G - Physics

01

N

G01N 33/68 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2486218

This invention relates to a method for identifying MS patients susceptible to type I-Interferon (IFN), in particular IFN-.szlig., and for monitoring IFN therapy in MS patients by determining TRAIL gene and/or protein expression as a marker.

L'invention concerne un procédé permettant d'identifier des patients atteints d'une sclérose en plaques (SEP) qui réagissent à l'interféron de type I (IFN), en particulier à l'IFN-.beta., ainsi que de surveiller un traitement par IFN chez des patients souffrant d'une SEP, par détermination de l'expression du gène et/ou de la protéine TRAIL en tant que marqueur.

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