C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/90 (2006.01) A61K 31/341 (2006.01) A61K 31/381 (2006.01) A61K 31/416 (2006.01) A61K 31/42 (2006.01) A61K 31/426 (2006.01) C07D 263/34 (2006.01) C07D 277/56 (2006.01) C07D 307/68 (2006.01) C07D 333/38 (2006.01)
Patent
CA 2584465
The invention relates to novel heterocyclic compounds of formula (I) wherein R1, D, W, T and T' have the meaning cited in the claim 1. Said compounds are SGK-inhibitors and can be used in the treatment of SGK-related diseases and disorders such as diabetes, obesity, metabolic syndrome (dyslipidemia), systemic and pulmonal hypertension, cardiovascular diseases and renal diseases, and generally for any kind of fibroses and inflammatory processes.
L'invention concerne de nouveaux composés hétérocycliques de formule (I) dans laquelle R1, D, W, T et T' sont tels que définis dans la première revendication. Ces composés sont des inhibiteurs de la kinase SGK et peuvent servir à traiter des maladies et des affections qui sont liées à la kinase SGK, à savoir le diabète, l'obésité, le syndrome métabolique (dyslipidémie), l'hypertension systémique et pulmonaire, les maladies cardiovasculaires, et les maladies rénales, et de manière générale, tout type de fibroses et de phénomènes inflammatoires.
Beier Norbert
Dorsch Dieter
Gericke Rolf
Lang Florian
Mederski Werner
Fetherstonhaugh & Co.
Merck Patent Gesellschaft Mit Beschraenkter Haftung
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