A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4162 (2006.01) A61K 31/00 (2006.01) A61K 31/506 (2006.01) A61P 19/10 (2006.01)
Patent
CA 2427551
The invention relates to the use of stimulators of soluble guanylate cyclase, in particular, compounds of formula (I), wherein: R1 represents a saturated or unsaturated optionally substituted C3-8 cycloalkyl or represents a saturated, unsaturated or partially unsaturated heterocyclyl, which has 3 to 8 members, contains 1-4 heteroatoms from the set N, O, S, SO, SO2, and which can be optionally substituted; R2 represents H or NH2. The invention also relates to the use of the salts, isomers and hydrates of said compounds in order to produce medicaments used for treating osteoporosis.
L'invention concerne l'utilisation pour produire un médicament employé dans le traitement de l'ostéoporose, de stimulateurs de la cyclase de guanylate soluble, notamment de composés de formule (I), dans laquelle R?1¿ désigne un cycloalkyle C¿3-8? saturé ou insaturé, éventuellement substitué ou un hétérocycle ayant entre 3 et 8 chaînons, saturé, insaturé ou partiellement insaturé, pouvant contenir entre 1 et 4 hétéroatomes de la série N, O, S, SO, SO¿2? et être éventuellement substitué ; R?2¿ désigne H ou NH¿2?. L'invention concerne également l'utilisation de leurs sels, isomères et hydrates.
Geiss Volker
Sander Erich
Stasch Johannes-Peter
Straub Alexander
Aktiengesellschaft Bayer
Fetherstonhaugh & Co.
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