Il-6/ds-sil-6r fusion protein

Details Il-6/ds-sil-6r fusion protein Il-6/ds-sil-6r fusion protein

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 38/20 (2006.01) A61K 48/00 (2006.01) A61P 19/02 (2006.01) A61P 31/18 (2006.01) A61P 37/00 (2006.01) C07K 14/54 (2006.01) C07K 14/705 (2006.01) C07K 14/715 (2006.01) C12N 15/12 (2006.01) C12N 15/24 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2456183

The present invention relates to a fusion protein comprising a functional IL-6 molecule and a functional DS-sIL-6R molecule. The present invention also relates to a nucleic acid encoding the fusion protein, methods for producing the fusion protein and the use of the fusion protein in the treatment of infectious diseases and inflammatory and immunological disorders.

L'invention concerne une protéine hybride comprenant une molécule IL-6 fonctionnelle et une molécule DS-sIL-6R fonctionnelle. L'invention concerne également un acide nucléique codant pour cette protéine hybride, des procédés de production de cette protéine hybride, et l'utilisation de cette protéine hybride dans le traitement de maladies infectieuses et inflammatoires ainsi que de troubles immunologiques.

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