Agglomerate formulations useful in dry powder inhalers

Details Agglomerate formulations useful in dry powder inhalers Agglomerate formulations useful in dry powder inhalers

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 9/72 (2006.01) A61K 31/58 (2006.01)

Patent

CA 2759041

Several embodiments of the present invention provide for an agglomerate useful for an agglomerate based dry powder inhaler comprising at least one active pharmaceutical agent, at least one additional functional excipient and at least one excipient, such as a binder. Useful at least one additional functional excipients include but are not limited to magnesium stearate, colloidal silica, silicon dioxide, sucrose stearate, L--leucine and combinations thereof.

Plusieurs modes de réalisation de la présente invention concernent un agglomérat utile pour un inhalateur à poudre sèche à base d'agglomérat comprenant au moins un agent pharmaceutique actif, au moins un excipient fonctionnel supplémentaire et au moins un excipient, tel qu'un liant. Un ou plusieurs excipients fonctionnels supplémentaires comprennent entre autres le stéarate de magnésium, la silice colloïdale, l'oxyde de silicium, le stéarate de sucrose, la L-leucine et leurs combinaisons.

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