Gene expression from the internal ribosome entry site (ires)...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/29 (2006.01) A01H 5/00 (2006.01) C07K 14/08 (2006.01) C12N 5/10 (2006.01) C12N 15/67 (2006.01) C12N 15/82 (2006.01)

Patent

CA 2418746

Polynucleotide sequence capable of directing translation initiation in a plant expression system in a cap-independent manner, wherein the polynucleotide sequence directs translation initiation from an AUG codon. In particular, the invention relates to a polynucleotide sequence which comprises the 5' UTR of Rhopalosiphum padi virus (RhPV) which comprises an internal ribosome enty site (IRES).

L'invention concerne un polynucléotide capable de mener l'initiation de traduction dans un système d'expression végétal indépendamment de la coiffe. Ce polynucléotide mène l'initiation de traduction à partir d'un codon AUG. L'invention concerne, notamment un polynucléotide renfermant le virus 5' UTR de Rhopalosiphum padi qui comprend une séquence IRES.

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