Combination for the therapy of benign prostatic hyperplasia

Details Combination for the therapy of benign prostatic hyperplasia Combination for the therapy of benign prostatic hyperplasia

A - Human Necessities

61

K

A61K 31/519 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/50 (2006.01) A61K 31/517 (2006.01) A61K 31/58 (2006.01) A61P 13/08 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2605224

The invention relates to a novel method for treating the symptoms of benign prostate hyperplasia. According to said method, the following substances are used simultaneously: (1) an .alpha.-1 adrenoceptor antagonist in a controlled releasing formulation or a 5-.alpha. reductase inhibitor, and (2) a cGMP PDE 5 inhibitor in a controlled releasing formulation or a cGMP PDE 5 inhibitor having a long half-life.

La présente invention concerne un nouveau procédé pour traiter les symptômes en cas d'hyperplasie bénigne de la prostate. A cette fin on utilise (1) un antagoniste de récepteur adrénergique a-1 dans une préparation à libération contrôlée ou un inhibiteur de la 5-a réductase et (2) un inhibiteur de cGMP PDE 5 dans une préparation à libération contrôlée ou un inhibiteur de cGMP PDE 5 présentant une demi-vie plus longue.

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