4-benzylaminoquinoline conjugates with bile acid and their...

C - Chemistry – Metallurgy – 07 – J

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C07J 43/00 (2006.01) A61K 31/575 (2006.01) A61K 31/58 (2006.01) A61P 1/16 (2006.01) C07J 9/00 (2006.01) C07J 41/00 (2006.01) C07J 75/00 (2006.01)

Patent

CA 2385445

The invention relates to substituted 4-benzylaminoquinolines of formula (I), wherein the radicals have the meanings given, and to their heteroanalogues, their pharmaceutically compatible salts and their physiologically functional derivatives. The invention also relates to methods for producing said compounds. These compounds are suitable for use e.g. as medicaments for preventing or treating gall stones.

L'invention concerne des 4-benzylaminoquinolines substituées et leurs hétéroanalogues, ainsi que leurs sels pharmaceutiquement compatibles et leurs dérivés physiologiquement fonctionnels. L'invention concerne également des composés de la formule (I) où les restes ont les significations données, ainsi que leurs sels physiologiquement compatibles, leurs dérivés physiologiquement fonctionnels et leurs procédés de production. Ces composés sont adaptés, par exemple, comme médicaments pour prévenir et traiter les calculs biliaires.

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