C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 327/34 (2006.01) A61K 31/16 (2006.01) C07C 69/618 (2006.01) C07C 69/65 (2006.01) C07C 211/49 (2006.01) C07C 219/10 (2006.01) C07D 207/16 (2006.01) C07D 209/28 (2006.01) C07D 233/64 (2006.01) C07D 277/06 (2006.01) C07D 277/14 (2006.01) C07D 295/088 (2006.01) C07D 309/30 (2006.01) C07D 401/12 (2006.01) C07D 407/04 (2006.01) C07D 417/12 (2006.01) C07D 473/08 (2006.01) C07D 495/04 (2006.01) C07D 499/32 (2006.01) C07F 9/38 (2006.01) C07H 15/252 (2006.01) C07H 17/07 (2006.01)
Patent
CA 2370406
Compounds or their salts of general formula (I): A-(B) wherein A = R-T1-, wherein R is the drug radical and T1 = (CO)t or (X)t', wherein X = O, S, NR1C, R1C is H or an alkyl having from 1 to 5 carbon atoms, or a free valence, t and t' are integers and equal to zero or 1, with the proviso that t = 1 when t' = 0; t = 0 when t' = 1; B = -TB-X2 wherein TB = (CO) when t = 0, TB = X when t' = -, X being as above defined; X2, monovalent radical, is such that the precursor drug of A and the precursor of B respectively meet the pharmacological tests described in the application.
La présente invention concerne des composés ou leurs sels représentés par la formule générale (I): A-(B). Dans cette formule A = R-T¿1?-, R est le radical du médicament et T¿1? = (CO)¿t? ou (X)¿t'?, X = O, S, NR¿1C?, R¿1C? est H ou un alkyle possédant de 1 à 5 atomes de carbone, ou une valence quelconque, t et t' sont des entiers égaux à 0 ou 1, sous la réserve que t = 1 lorsque t' = 0; t = 0 lorsque t' = 1; B = -T¿B?-X¿2?, T¿B? = (CO) lorsque t = 0, T¿B? = X lorsque t' = 0, X étant défini comme ci-dessus; X¿2?, radical monovalent, est tel que les précurseurs du médicament de A et de B respectivement satisfassent aux tests pharmacologiques de la description.
Gowling Lafleur Henderson Llp
Nicox S.a.
LandOfFree
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