Placental niche and use thereof to culture stem cells

Details Placental niche and use thereof to culture stem cells Placental niche and use thereof to culture stem cells

C - Chemistry, Metallurgy

12

N

C12N 5/06 (2006.01)

Patent

CA 2654716

The present invention provides methods for culturing, expanding and differentiating stem cells, particularly human embryonic stem cells. The methods comprise culturing the stem cells for a period of time on a collagen biofabric, particularly a collagen biofabric derived from the amniotic membrane, chorion, or both, from mammalian placenta.

La présente invention concerne des méthodes pour cultiver, développer et différencier des cellules souches et particulièrement des cellules souches embryonnaires humaines. Les méthodes consistent à cultiver les cellules souches pendant une certaine période sur un bio-tissu collagène, en particulier un bio-tissu collagène dérivé d'une membrane amniotique et/ou d'un chorion provenant d'un placenta mammifère.

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