3,4,n-trisubstituted-4,5-dihydro-1h-pyrazole-1-carboxamides...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/04 (2006.01) A01N 47/38 (2006.01) C07D 213/50 (2006.01) C07D 213/60 (2006.01) C07D 213/61 (2006.01) C07D 213/85 (2006.01) C07D 215/18 (2006.01) C07D 237/06 (2006.01) C07D 237/12 (2006.01) C07D 239/26 (2006.01) C07D 239/30 (2006.01) C07D 241/10 (2006.01) C07D 241/12 (2006.01) C07D 241/16 (2006.01) C07D 403/04 (2006.01)

Patent

CA 2065746

ABSTRACT 3,4,N-Triaryl-4,5-dihydro-1H-pyrazole-1- -carboxamide compounds having an aryl moiety in the 4-position that is an optionally substituted pyridinyl, pyrimidinyl, pyridazinyl, pyrazinyl, or quinolinyl moiety and aryl moieties in the 3-position and the N-position that are optionally substituted phenyl, pyridinyl, pyrimidinyl, pyridazinyl, pyrazinyl, or quinolinyl moieties, such as N-(4-chlorophenyl)-4,5- -dihydro-3-(4-fluorophenyl)-4-(5-triflucromethyl-2- -pyridinyl) 1H-pyrazole-1-carboxamide, were prepared and found to possess insecticidal utility. 1,2-Diaryl- ethanone compounds were converted to 1,2-diaryl-2- -propen-1-one compounds by treatment with bis(dimethyl- amino)methane, the 1,2-diaryl-2-propen-1-one compounds were converted to 3,4-diaryl-4,5-dihydro-lH-pyrazole compounds by treatment with hydrazine, and the 3,4-di- aryl-4,5-dihydro-1H-pyrazole compounds were converted to the insecticidal subject compounds by treatment with an aryl isocyanate. 50,062A-F

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