A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/22 (2006.01) A01N 37/18 (2006.01) A01N 43/04 (2006.01) A61K 47/28 (2006.01) A61K 48/00 (2006.01) C12N 15/87 (2006.01) C12N 15/88 (2006.01)
Patent
CA 2456977
The invention relates to compositions and methods for a one-step synthetic technique for making cationic steroid or cationic drug molecules for use as delivery vehicles. The invention further relates to methods for using cationic steroid molecules in lipofection or transfection, delivery of drugs, and for treatment of inflammation and other diseases and disorders. The invention also relates to cationic steroid prodrugs and cationic prodrugs and to methods of modifying drugs.
La présente invention concerne des compositions et des procédés de synthèse en une étape permettant de préparer des molécules de stéroïdes cationiques ou des molécules de médicaments cationiques destinées à être utilisées en tant que vecteurs. Cette invention concerne également des méthodes d'utilisation des molécules de stéroïdes cationiques pour la lipofection ou la transfection, l'apport de médicaments et pour le traitement de l'inflammation et d'autres maladies et troubles; ainsi que des promédicaments stéroïdiens cationiques et des promédicaments cationiques, et des procédés de modification des médicaments.
Diamond Scott L.
Gruneich Jeffrey
Gowling Lafleur Henderson Llp
The Trustees Of The University Of Pennsylvania
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