Bridged aza-bicyclic derivatives as substance p antagonists

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 221/22 (2006.01) A61K 31/435 (2006.01) C07C 271/22 (2006.01) C07D 205/085 (2006.01) C07D 213/55 (2006.01) C07D 307/54 (2006.01) C07D 333/24 (2006.01) C07D 401/00 (2006.01) C07D 405/00 (2006.01) C07D 409/00 (2006.01) C07D 413/00 (2006.01) C07D 417/00 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2134964

The present invention relates to bridged aza-bicyclic derivatives of formula (I). These novel compounds are useful in the treatment of inflammatory and central nervous system disorders, as well as other disorders. The invention also relates to novel intermediates used in the synthesis of compounds of formula (I).

La présente invention concerne des dérivés aza-bicycliques pontés de formule (I). Ces nouveaux composés sont utiles dans le traitement des maladies inflammatoires et des affections du système nerveux central ainsi que d'autres maladies. L'invention concerne également les nouveaux intermédiaires utilisés dans la synthèse des composés de formule (I).

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