Use of modulators of nicotinic receptors for treatment of...

A - Human Necessities – 61 – K

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A61K 31/55 (2006.01) A61K 31/465 (2006.01) A61P 25/14 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2475655

A method for treating the effects of low LDL-cholesterol values in the brain on cognitive performance or other central nervous system functions by modulating nicotinic receptors by administering an effective amount of a nicotinic allosteric potentiator, an acetylcholinesterase inhibitor, nicotine, a nicotinic agonist or a mixture thereof to a patient in need of such modulation.

L'invention concerne une méthode de traitement des effets de faibles valeurs de cholestérol LDL dans le cerveau sur la performance cognitive ou d'autres fonctions du système nerveux central, par modulation des récepteurs nicotiniques par administration d'une quantité efficace d'un potentialisateur allostérique, d'un inhibiteur d'acétylcholinestérase, de nicotine, d'un agoniste nicotinique ou d'un mélange de ceux-ci à un patient nécessitant une telle modulation.

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