Gamma-secretase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 233/54 (2006.01) A61K 31/4164 (2006.01) A61K 31/4178 (2006.01) A61K 31/4196 (2006.01) A61K 31/427 (2006.01) A61K 31/433 (2006.01) A61P 25/28 (2006.01) C07D 249/08 (2006.01) C07D 409/12 (2006.01) C07D 417/04 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2539042

Compounds of formula: (I) are potent inhibitors of gamma-secretase and hence find use in treatment or prevention of diseases associated with deposition of .beta.-amyloid.

La présente invention concerne des composés représentés par la formule (I). Ces composés sont des inhibiteurs puissants de gamma-sécrétase et, par conséquent ils conviennent pour le traitement ou la prévention de maladies associées au dépôt d'amyloïde B.

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