Methods and compounds for treating neurologic or...

A - Human Necessities – 61 – K

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A61K 31/495 (2006.01) A61K 31/10 (2006.01) A61K 31/22 (2006.01) C12Q 1/34 (2006.01)

Patent

CA 2437353

A method of treating a neurologic or neuropsychiatric disorder or disease in a mammal is provided. The method comprises administering a fatty acid amide hydrolase inhibitor in an amount sufficient to inhibit deamidation of a fatty acid amide. A method of identifying a fatty acid amide hydrolase inhibitor useful in the treatment of a neurologic or neuropsychiatric disorder is also provided. A method of identifying a fatty acid amide or fatty acid useful in the treatment of a neurologic or neuropsychiatric disorder is also provided.

L'invention concerne un procédé relatif au traitement de troubles ou de maladies neurologiques ou neuropsychiatriques chez un mammifère. Ce procédé consiste à administrer un inhibiteur d'hydrolase d'amide d'acide gras en quantité suffisante pour inhiber la désamidisation d'un amide d'acide gras. L'invention concerne également un procédé relatif à l'identification d'un inhibiteur d'hydrolase d'amide d'acide gras utile pour le traitement d'un trouble neurologique ou neuropsychiatrique. L'invention concerne par ailleurs un procédé relatif à l'identification d'un amide d'acide gras ou d'un acide gras utile pour le traitement d'un trouble neurologique ou neuropsychiatrique.

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