C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07H 21/04 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C12N 9/00 (2006.01) C12N 9/64 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2395787
The present invention relates to novel proteins. More specifically, isolated nucleic acid molecules are provided encoding novel polypeptides. Novel polypeptides and antibodies that bind to these polypeptides are provided. Also provided are vectors, host cells, and recombinant and synthetic methods for producing human polynucleotides and/or polypeptides, and antibodies. The invention further relates to diagnostic and therapeutic methods useful for diagnosing, treating, preventing and/or prognosing disorders related to these novel polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of polynucleotides and polypeptides of the invention. The present invention further relates to methods and/or compositions for inhibiting or enhancing the production and function of the polypeptides of the present invention.
La présente invention concerne de nouvelles protéines. Plus spécifiquement, l'invention concerne des molécules d'acides nucléiques isolées codant de nouveaux polypeptides. L'invention concerne également des nouveaux polypeptides et des anticorps se fixant à ces polypeptides. De plus, l'invention concerne des vecteurs, des cellules hôtes ainsi que des méthodes de recombinaison et de synthèse permettant la production de polynucléotides et/ou polypeptides ainsi que des anticorps humains. L'invention concerne aussi des méthodes diagnostiques et thérapeutiques utiles pour diagnostiquer, traiter, prévenir et/ou pronostiquer des troubles liés à ces nouveaux polypeptides. L'invention concerne aussi des méthodes de criblage permettant d'identifier des agonistes et des antagonistes de polynucléotides et de polypeptides de l'invention. En outre l'invention concerne des méthodes et/ou des compositions destinées à inhiber ou à augmenter la production et la fonction des polypeptides de la présente invention.
Barash Steven C.
Rosen Craig A.
Ruben Steven M.
Barash Steven C.
Human Genome Sciences Inc.
Mbm & Co.
Rosen Craig A.
Ruben Steven M.
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