C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/86 (2006.01) A61K 31/70 (2006.01) A61K 35/12 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C12N 5/10 (2006.01) C12N 7/01 (2006.01) C12N 15/18 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2184408
Recombinant adenoviruses comprising a heterologous DNA sequence coding for glial maturation factor beta (GMF-.beta.), preparation thereof, and uses thereof, in particular for treating and/or preventing degenerative neurological diseases or central nervous system tumours.
La présente invention concerne des adénovirus recombinants comportant une séquence d'ADN hétérologue codant pour le facteur de maturation des cellules gliales type béta (GMF-.beta.), leur préparation, et leur utilisation, en particulier pour le traitment et/ou la prévention des maladies neurodégératives ou des tumeurs du système nerveux central.
Barneoud Pascal
Delaere Pia
Perricaudet Michel
Pradier Laurent
Vigne Emmanuelle
Rhone-Poulenc Rorer S.a.
Robic
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