Aromatic derivatives as hiv aspartyl protease inhibitors

Details Aromatic derivatives as hiv aspartyl protease inhibitors Aromatic derivatives as hiv aspartyl protease inhibitors

C - Chemistry, Metallurgy

07

C

C07C 301/02 (2006.01) A61K 31/455 (2006.01) A61K 31/5375 (2006.01) C07C 311/40 (2006.01) C07D 207/34 (2006.01) C07D 213/81 (2006.01) C07D 233/90 (2006.01) C07D 237/24 (2006.01) C07D 295/215 (2006.01) C07D 307/24 (2006.01)

Patent

CA 2435908

The present invention provides HIV aspartyl protease inhibitors of the formula; (see formula I) and when the compound of formula I comprises an amino group, pharmaceutically acceptable ammonium salts thereof, wherein n is 3 or 4, wherein R1 may be, for example, iso-butyl, wherein X and Y, same or different, may be, for example, NH2 and F, and wherein R2 and R3 are as defined herein.

La présente invention porte sur des inhibiteurs d'aspartyl protéases du VIH présentant la formule I. Le composé de la formule I comprend un groupe amino, des sels d'ammonium pharmaceutiquement acceptables dudit composé, où n est 3 ou 4, où R1 peut être, par exemple, un groupe iso-butyle, où X et Y, identiques ou différents, peuvent être, par exemple, NH2 et F, et où R2 et R3 sont comme il a été défini dans la présente.

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