Florfenicol prodrug having improved water solubility

C - Chemistry – Metallurgy – 07 – F

Patent

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Details

C07F 9/09 (2006.01) A61K 9/08 (2006.01) A61K 31/661 (2006.01) A61P 31/04 (2006.01) C07F 9/547 (2006.01)

Patent

CA 2550660

The present invention discloses phosphate esters of florfenicol (prodrugs) and florfenicol analogs having superior water solubility that are hydrolyzed to florfenicol or the respective florfenicol analog in vivo, upon administration to an animal.

L'invention concerne des esters de phosphate de florfénicol (promédicament) ainsi que des analogues de florénicol dotés d'une hydrosolubilité supérieure qui sont hydrolysés en florfénicol, ou l'analogue de florfénicol respectif, in vivo, après administration à un animal.

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