Glycosphingolipids with a group capable of coupling in the...

Details Glycosphingolipids with a group capable of coupling in the... Glycosphingolipids with a group capable of coupling in the...

C - Chemistry, Metallurgy

07

H

167/199, 530/15.

C07H 15/10 (2006.01) A61K 31/70 (2006.01) C07H 15/04 (2006.01) C07K 2/00 (2006.01)

Patent

CA 2003662

The invention relates to the chemical modification of the sphingoid portions of glycosphingolipids. It has been possible by a series of reactions to introduce an amino group in the position of the carbon double-bond in the sphingoid portion after elimination of the long-chain aldehyde. Glycosphingolipids of the formula (2) and (3), where X and Y denote a group capable of coupling, are suitable for coupling to other molecules, preferably proteins. X preferably represents NH2, and Y preferably Image

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